Acetylcholinesterase Inhibition by Flavonoids from Agrimonia pilosa

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Acetylcholinesterase inhibition by flavonoids from Agrimonia pilosa.

In a bioassay-guided search for acetylcholinesterase (AChE) inhibitors from 180 medicinal plants, an ethyl acetate extract of whole plants of Agrimonia pilosa ledeb yielded tiliroside (1), 3-methoxy quercetin (2), quercitrin (3) and quercetin (4). We report herein for the first time that all four flavonol compounds showed significant inhibitory effects on AChE, particularly quercetin (4), which...

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ژورنال

عنوان ژورنال: Molecules

سال: 2007

ISSN: 1420-3049

DOI: 10.3390/12092130